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Category: Papers

Papers

Covalent Targeting of Splicing in T cells

25 Nov 202429 Apr 2025
Excited to see the final version of our manuscript out in Cell Chemical Biology. In this study, we investigate the mechanism of action of an immunosuppressive small-molecule electrophile, which targets…
Papers…

Stereochemical diversity as a source of discovery in chemical biology

31 May 2022
Our first review/perspective is out! Here we look into the role of stereochemistry in screening library design, prioritization of actionable targets, and molecular complexity of FDA approved drugs. It was…

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